Volume 1, Issue 2, July 2015, Page: 22-26
Prognostic Ability of Simplified Pulmonary Embolism Severity Index (PESI) Score in Real World: A Brief Report
Luca Masotti, Internal Medicine, Santa Maria Nuova Hospital, Florence, Italy; Internal Medicine, Cecina Hospital, Livorno, Italy; Internal Medicine, Santa Maria Nuova Hospital, Florence, Italy
Grazia Panigada, Internal Medicine, Pescia Hospital, Pistoia, Italy
Giancarlo Landini, Internal Medicine, Santa Maria Nuova Hospital, Florence, Italy
Filippo Pieralli, Internal Medicine, Careggi Hospital, Florence, Italy
Francesco Corradi, Internal Medicine, Careggi Hospital, Florence, Italy
Salvatore Lenti, Internal Medicine, Arezzo Hospital, Arezzo, Italy
Rino Migliacci, Internal Medicine, Cortona Hospital, Arezzo, Italy
Carlo Nozzoli, Internal Medicine, Careggi Hospital, Florence, Italy
Maddalena Grazzini, Internal Medicine, Careggi Hospital, Florence, Italy
Lucia Ciucciarelli, Internal Medicine, Careggi Hospital, Florence, Italy
Alessandro Morettini, Internal Medicine, Careggi Hospital, Florence, Italy
Sara Bucherelli, Internal Medicine, Careggi Hospital, Florence, Italy
Alessandra Petrioli, Internal Medicine, Careggi Hospital, Florence, Italy
Carlotta Casati, Internal Medicine, Careggi Hospital, Florence, Italy
Mario Felici, Internal Medicine, Arezzo Hospital, Arezzo, Italy
Luciano Ralli, Internal Medicine, Arezzo Hospital, Arezzo, Italy
Stefano Arrigucci, Internal Medicine, Arezzo Hospital, Arezzo, Italy
Laila Teghini, Internal Medicine, Pescia Hospital, Pistoia, Italy
Giovanni Antonio Porciello, Internal Medicine, Cortona Hospital, Arezzo, Italy
Stefano Spolveri, Internal Medicine, Borgo San Lorenzo Hospital, Florence, Italy
Daniele Baldoni, Internal Medicine, Borgo San Lorenzo Hospital, Florence, Italy
Anna Frullini, Internal Medicine, Borgo San Lorenzo Hospital, Florence, Italy
Barbara Cimolato, Internal Medicine, Santa Maria Nuova Hospital, Florence, Italy
Gianni Lorenzini, Internal Medicine, Cecina Hospital, Livorno, Italy
Alessandro Pampana, Internal Medicine, Cecina Hospital, Livorno, Italy
Guidantonio Rinaldi, Internal Medicine, Barga Hospital, Lucca, Italy
Maria Chiara Bertieri, Internal Medicine, Barga Hospital, Lucca, Italy
Raffaele Laureano, Internal Medicine, Santa Maria Annunziata Hospital, Florence, Italy
Stefano Tatini, Internal Medicine, Santa Maria Annunziata Hospital, Florence, Italy
Alberto Fortini, Internal Medicine, San Giovanni di Dio Hospital, Florence, Italy
Chiara Angotti, Internal Medicine, San Giovanni di Dio Hospital, Florence, Italy
Valerio Verdiani, Internal Medicine, Grosseto Hospital, Grosseto, Italy
Anna Maria Romagnoli, Internal Medicine, Grosseto Hospital, Grosseto, Italy
Irene Cascinelli, Internal Medicine, Grosseto Hospital, Grosseto, Italy
Alberto Camaiti, Internal Medicine, Livorno Hospital, Livorno, Italy
Nicola Mumoli, Internal Medicine, Livorno Hospital, Livorno, Italy
Marco Cei, Internal Medicine, Livorno Hospital, Livorno, Italy
Stefano Giuntoli, Internal Medicine, Livorno Hospital, Livorno, Italy
Massimo Alessandri, Internal Medicine, Massa Marittima Hospital, Grosseto, Italy
Alessandro De Palma, Internal Medicine, Massa Marittima Hospital, Grosseto, Italy
Maurizio Manini, Internal Medicine, Orbetello Hospital, Grosseto, Italy
Veronica De Crescenzo, Internal Medicine, Orbetello Hospital, Grosseto, Italy
Michele Piacentini, Internal Medicine, Piombino Hospital, Livorno, Italy
Carlo Passaglia, Internal Medicine, Cisanello Hospital, Pisa, Italy
Giancarlo Tintori, Internal Medicine, Cisanello Hospital, Pisa, Italy
Carlo Palermo, Internal Medicine, Campostaggia Hospital, Siena, Italy
Alba Dainelli, Internal Medicine, Campostaggia Hospital, Siena, Italy
Roberto Andreini, Internal Medicine, Pontedera Hospital, Florence, Italy
Giuseppa Levantino, Internal Medicine, Pontedera Hospital, Florence, Italy
Plinio Fabiani, Internal Medicine, Portoferraio Hospital, Livorno, Italy
Lucia Raimondi, Internal Medicine, Portoferraio Hospital, Livorno, Italy
Massimo Di Natale, Internal Medicine, Prato Hospital, Prato, Italy
Filippo Risaliti, Internal Medicine, Prato Hospital, Prato, Italy
Rossella Nassi, Internal Medicine, San Sepolcro Hospital, Arezzo, Italy
Roberta Mastriforti, Internal Medicine, San Sepolcro Hospital, Arezzo, Italy
Roberto Cappelli, Internal Medicine, Le Scotte Hospital, Siena, Italy
Michele Voglino, Internal Medicine, Le Scotte Hospital, Siena, Italy
Paola Lambelet, Internal Medicine, Viareggio Hospital, Viareggio, Italy
Stefano Fascietti, Internal Medicine, Viareggio Hospital, Viareggio, Italy
Adriano Cioppi, Internal Medicine, Viareggio Hospital, Viareggio, Italy
Valentina Carli, Internal Medicine, Viareggio Hospital, Viareggio, Italy
Alessandro Tafi, Internal Medicine, Volterra Hospital, Volterra, Italy
Simone Meini, Internal Medicine, Volterra Hospital, Volterra, Italy
Emilio Santoro, Internal Medicine, Bibbiena Hospital, Bibbiena, Italy
Claudia Rosi, Internal Medicine, Bibbiena Hospital, Bibbiena, Italy
Received: Jun. 5, 2015;       Accepted: Jun. 24, 2015;       Published: Jun. 25, 2015
DOI: 10.11648/j.ijcems.20150102.14      View  2868      Downloads  60
Abstract
Background and aim: Prognostic stratification of acute pulmonary embolism (PE) represents the cornerstone of modern management of this potentially life-threatening disease. In the latest years, a lot of clinical prognostic models have been validated. However, these are yet underused in clinical practice, especially in real world populations. The aim of our study was to test the prognostic ability of the Simplified Pulmonary Embolism Severity Index (sPESI) score in a real world population. Methods: Data records of 452 patients that were discharged for acute PE from 28 Internal Medicine wards of Tuscany (Italy) were retrospectively analysed. sPESI was calculated in the identical manner as the original study. Prognostic ability of sPESI score for predicting in-hospital all-cause and PE-related mortality was tested by using Areas under Receiver Operating Characteristics (ROC) curve (AUC). Results: 15.2% of patients were classified as sPESI score 0, whereas 84.8% were classified as sPESI ≥ 1. All causes of in-hospital mortality were 10.95% (5.75% PE-related) in patients with sPESI score ≥ 1 and 0% (0% PE-related) in sPESI score 0. AUC for all causes of mortality was 0.694 (95% CI: 0.650-0.736), whereas it was 0.702 (95% CI: 0.657-0.743) for PE-related mortality. Conclusion: In a real world population, sPESI is a good prognosticator for all causes of in-hospital and PE-related mortality and its use should be encouraged.
Keywords
Pulmonary Embolism, Prognosis, PESI Score
To cite this article
Luca Masotti, Grazia Panigada, Giancarlo Landini, Filippo Pieralli, Francesco Corradi, Salvatore Lenti, Rino Migliacci, Carlo Nozzoli, Maddalena Grazzini, Lucia Ciucciarelli, Alessandro Morettini, Sara Bucherelli, Alessandra Petrioli, Carlotta Casati, Mario Felici, Luciano Ralli, Stefano Arrigucci, Laila Teghini, Giovanni Antonio Porciello, Stefano Spolveri, Daniele Baldoni, Anna Frullini, Barbara Cimolato, Gianni Lorenzini, Alessandro Pampana, Guidantonio Rinaldi, Maria Chiara Bertieri, Raffaele Laureano, Stefano Tatini, Alberto Fortini, Chiara Angotti, Valerio Verdiani, Anna Maria Romagnoli, Irene Cascinelli, Alberto Camaiti, Nicola Mumoli, Marco Cei, Stefano Giuntoli, Massimo Alessandri, Alessandro De Palma, Maurizio Manini, Veronica De Crescenzo, Michele Piacentini, Carlo Passaglia, Giancarlo Tintori, Carlo Palermo, Alba Dainelli, Roberto Andreini, Giuseppa Levantino, Plinio Fabiani, Lucia Raimondi, Massimo Di Natale, Filippo Risaliti, Rossella Nassi, Roberta Mastriforti, Roberto Cappelli, Michele Voglino, Paola Lambelet, Stefano Fascietti, Adriano Cioppi, Valentina Carli, Alessandro Tafi, Simone Meini, Emilio Santoro, Claudia Rosi, Prognostic Ability of Simplified Pulmonary Embolism Severity Index (PESI) Score in Real World: A Brief Report, International Journal of Clinical and Experimental Medical Sciences. Vol. 1, No. 2, 2015, pp. 22-26. doi: 10.11648/j.ijcems.20150102.14
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