Volume 2, Issue 2, March 2016, Page: 26-30
Effects of β-Glucan on Natural Killer Cells in Patients Recovering from Cancer Treatment: Clinical Trial
Josef Richter, Health Institute (Zdravotni ustav se sidlem) of Usti nad Labem, Usti nad Labem, Czech Republic
Vlastimil Kral, Health Institute (Zdravotni ustav se sidlem) of Usti nad Labem, Usti nad Labem, Czech Republic
Jitka Pohorska, Health Institute (Zdravotni ustav se sidlem) of Usti nad Labem, Usti nad Labem, Czech Republic
Lucie Rajnohova Dobiasova, Health Institute (Zdravotni ustav se sidlem) of Usti nad Labem, Usti nad Labem, Czech Republic
Vaclav Vetvicka, University of Louisville, Department of Pathology, Louisville, KY, USA
Received: Mar. 8, 2016;       Accepted: Mar. 11, 2016;       Published: Apr. 25, 2016
DOI: 10.11648/j.ijcems.20160202.12      View  3309      Downloads  85
Abstract
Glucan is the most studied immunomodulator. Among its properties, effects on cancer are the closest to clinical use. In our study, we evaluated the effects of short-term supplementation with glucan on NK cells in patients recovering from different types of cancer treatment. NK cells represent a distinct sub-population of lymphocytes endowed with the capacity to kill tumor cells without prior sensitization and form one of the most important defense mechanisms against cancer. To measure the numbers of NK cells, flow cytometer measuring four colors was used. Using a double-blind, placebo-controlled clinical trial, we found that adding glucan to the diet strongly increased the number of NK cells in blood.
Keywords
Cancer, Glucan, NK Cells, Immunity, Lymphocytes
To cite this article
Josef Richter, Vlastimil Kral, Jitka Pohorska, Lucie Rajnohova Dobiasova, Vaclav Vetvicka, Effects of β-Glucan on Natural Killer Cells in Patients Recovering from Cancer Treatment: Clinical Trial, International Journal of Clinical and Experimental Medical Sciences. Vol. 2, No. 2, 2016, pp. 26-30. doi: 10.11648/j.ijcems.20160202.12
Copyright
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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